Robert H Mach Selected Research

benzamide

1/2017	Design and Investigation of a [18F]-Labeled Benzamide Derivative as a High Affinity Dual Sigma Receptor Subtype Radioligand for Prostate Tumor Imaging.
11/2016	Comparative evaluation of 4 and 6-carbon spacer conformationally flexible tetrahydroisoquinolinyl benzamide analogues for imaging the sigma-2 receptor status of solid tumors.
1/2013	Quantitative receptor-based imaging of tumor proliferation with the sigma-2 ligand [(18)F]ISO-1.
7/2007	Fluorine-18-labeled benzamide analogues for imaging the sigma2 receptor status of solid tumors with positron emission tomography.
6/2006	Synthesis and in vivo evaluation of 2 high-affinity 76Br-labeled sigma2-receptor ligands.

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Robert H Mach Research Topics

Disease

64	Neoplasms (Cancer) 01/2022 - 10/2006
13	Parkinson Disease (Parkinson's Disease) 08/2021 - 05/2009
13	Breast Neoplasms (Breast Cancer) 01/2020 - 07/2005
9	Alzheimer Disease (Alzheimer's Disease) 09/2020 - 11/2009
9	Pancreatic Neoplasms (Pancreatic Cancer) 01/2017 - 07/2007
8	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 01/2012
7	Neuroinflammatory Diseases 01/2019 - 05/2015
6	Ovarian Neoplasms (Ovarian Cancer) 01/2022 - 03/2014
5	Inflammation (Inflammations) 01/2021 - 01/2012
5	Schizophrenia (Dementia Praecox) 01/2019 - 08/2009
4	Substance-Related Disorders (Drug Abuse) 01/2019 - 01/2018
4	Cocaine-Related Disorders (Cocaine Addiction) 12/2013 - 02/2002
3	Neuroblastoma 02/2021 - 01/2019
3	Synucleinopathies 01/2021 - 03/2020
3	Dementia (Dementias) 09/2020 - 10/2010
3	Nervous System Diseases (Neurological Disorders) 10/2016 - 11/2010
3	Adenocarcinoma 07/2014 - 07/2007
2	Dyskinesias (Dyskinesia) 05/2021 - 05/2009
2	Glioblastoma (Glioblastoma Multiforme) 02/2021 - 07/2013
2	Bacterial Infections (Bacterial Infection) 11/2019 - 01/2017
2	Carcinoma (Carcinomatosis) 01/2017 - 01/2013
2	Triple Negative Breast Neoplasms 01/2017 - 11/2015
2	Dystonia (Limb Dystonia) 01/2016 - 01/2011
2	Neoplasm Metastasis (Metastasis) 08/2014 - 02/2013
2	Cognitive Dysfunction 01/2014 - 03/2006
2	Brain Neoplasms (Brain Tumor) 07/2013 - 12/2010
2	Glioma (Gliomas) 07/2013 - 02/2007
2	Necrosis 01/2012 - 07/2005
1	Neoplasm Micrometastasis 01/2020
1	DNA Repair-Deficiency Disorders (Chromosome Instability Syndromes) 01/2018

Drug/Important Bio-Agent (IBA)

35	LigandsIBA 05/2021 - 07/2005
22	sigma-2 receptorIBA 01/2021 - 07/2007
16	Proteins (Proteins, Gene)FDA Link 12/2020 - 04/2009
14	Pharmaceutical PreparationsIBA 12/2020 - 02/2009
11	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2022 - 01/2016
11	Biomarkers (Surrogate Marker)IBA 01/2022 - 06/2012
9	Dopamine Receptors (Dopamine Receptor)IBA 05/2021 - 05/2009
7	Biological ProductsIBA 07/2020 - 02/2002
7	SV119IBA 01/2017 - 07/2007
6	EnzymesIBA 01/2020 - 01/2013
6	Amyloid (Amyloid Fibrils)IBA 05/2015 - 03/2006
5	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 01/2022 - 02/2017
5	Dopamine (Intropin)FDA LinkGeneric 10/2018 - 08/2006
5	benzamideIBA 01/2017 - 06/2006
4	Poly Adenosine Diphosphate RiboseIBA 01/2022 - 01/2020
4	SynucleinsIBA 12/2020 - 01/2013
4	Dopamine D3 ReceptorsIBA 01/2019 - 11/2013
4	CaspasesIBA 01/2017 - 07/2007
4	PPAR gammaIBA 01/2012 - 10/2006
3	ChromatinIBA 01/2021 - 01/2019
3	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2019 - 07/2014
3	olaparibIBA 08/2018 - 03/2014
3	Carbon-11IBA 01/2018 - 07/2005
3	Fluorine-18IBA 01/2018 - 12/2010
3	SW IV-134IBA 01/2017 - 03/2014
3	Gemcitabine FDA Link 01/2017 - 03/2009
2	Levodopa (L Dopa)FDA LinkGeneric 05/2021 - 05/2009
2	Oxidopamine (6 Hydroxydopamine)IBA 05/2021 - 05/2009
2	alpha-SynucleinIBA 01/2021 - 11/2018
2	RadiopharmaceuticalsIBA 12/2020 - 01/2020
2	Fluorescent Dyes (Fluorescent Probes)IBA 03/2020 - 12/2011
2	Thymidine Monophosphate (TMP)IBA 01/2020 - 01/2017
2	Anti-Bacterial Agents (Antibiotics)IBA 11/2019 - 01/2017
2	Glutamine (L-Glutamine)FDA Link 03/2019 - 01/2017
2	AZD2461IBA 01/2019 - 08/2018
2	Superoxides (Superoxide)IBA 01/2018 - 07/2014
2	Antineoplastic Agents (Antineoplastics)IBA 01/2017 - 02/2013
2	Caspase 3 (Caspase-3)IBA 01/2016 - 06/2015
2	Doxorubicin (Adriamycin)FDA LinkGeneric 07/2014 - 02/2009
2	Peptides (Polypeptides)IBA 07/2014 - 03/2014
2	PeptidomimeticsIBA 07/2014 - 03/2014
2	PropionatesIBA 07/2013 - 12/2010
2	Amino Acids FDA Link 07/2013 - 12/2010
2	Dopamine Agonists (Dopamine Agonist)IBA 08/2009 - 05/2009
1	Investigational DrugsIBA 01/2022
1	Neuroprotective AgentsIBA 08/2021
1	Death Domain ReceptorsIBA 02/2021
1	Immune Checkpoint InhibitorsIBA 02/2021
1	B7-H1 AntigenIBA 02/2021
1	Intrinsically Disordered ProteinsIBA 01/2021
1	Inosine Diphosphate (IDP)IBA 01/2021
1	Adenosine Diphosphate (ADP)IBA 12/2020
1	Adenosine Diphosphate Ribose (ADP-Ribose)IBA 12/2020
1	Apolipoproteins E (ApoE)IBA 09/2020
1	CholesterolIBA 07/2020
1	Estrogens (Estrogen)FDA Link 01/2019
1	alovudineIBA 01/2019
1	palbociclibIBA 01/2019
1	Fulvestrant (Faslodex)FDA Link 01/2019
1	Radioisotopes (Radionuclides)IBA 01/2019
1	Estrogen ReceptorsIBA 01/2019
1	GABA-A Receptors (GABA(A) Receptor)IBA 01/2019
1	Cyclin-Dependent Kinase 4IBA 01/2019
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 08/2018
1	BenzamidesIBA 03/2018

Therapy/Procedure

29	Therapeutics 08/2021 - 02/2007
5	Drug Therapy (Chemotherapy) 01/2017 - 02/2007
1	Immunotherapy 02/2021
1	Ligation 01/2021
1	Precision Medicine 12/2020